α-GPC 98% HPLC Powder - Premium Nootropic Ingredient with Superior Bioavailability for Cognitive & Sports Nutrition Solutions
Xi'an Jiayuan Bio-tech delivers pharmaceutical-grade α-GPC at 98% purity, backed by over 20 years of botanical extract manufacturing expertise and ISO, SGS, and HALAL certifications. Our facility has two manufacturing lines that meet GMP standards and rigorous HPLC testing procedures, to guaranty CAS 28319-77-9 compliance and consistent product quality from batch to batch. We have 30 million RMB registered capital, 30 specialist technical experts, we have the large volume inventory and factory direct price. This water-soluble derivative of choline phospholipid peaks in blood concentration in 1 hour and easily penetrates the blood-brain barrier, making it appropriate for use in cognitive health formulations, sports nutrition products and mood support supplements.
What Is α-GPC?
Alpha-Glyceryl Phosphoryl Choline is a natural choline molecule obtained from soy or sunflower lecithin by enzymatic deacylation. Compared to ordinary choline salts, this substance delivers twofold metabolic advantages.
Upon oral ingestion, it is hydrolyzed in the small intestine to choline and glycerol-3-phosphate. Choline is a key component of acetylcholine, which is necessary for memory, attention, and muscular contraction. Glycerol-3-phosphate is used in the creation of phospholipids and for cellular energy generation. This dual action mechanism targets both neurotransmission and membrane integrity.
Because of its low molecular weight it is rapidly absorbed and distributed in tissues including brain, liver and kidney. This higher bioavailability makes it unique from citicoline and choline bitartrate in formulation applications.
Functions
Enhancing Cognitive Function
Meta-analyses demonstrate that the medication enhances cognitive performance in people with cerebrovascular impairment. A 6-month trial of 1200 mg/day showed a substantial improvement in cognition in people with amnestic moderate cognitive impairment, results that were sustained 7 to 9 months after therapy.
Regular users had a lower chance of developing Alzheimer's disease in large cohort studies of over half a million people aged over 40.
Maximizing Athletic Performance
Clinical investigations have shown meaningful strength increases. Supplemented 600 mg daily for six days, leading to a considerable improvement in lower limb strength. Vertical jump height and muscular power production increased with a 7-day regimen of 250 mg/day.
Peak muscular strength and explosive power increased in trained athletes taking 315-630 mg before exercising.
Mood Regulation Support
Two-week supplementation at 400 mg/day increased motivation levels in healthy subjects. Post-stroke depression patients receiving 600 mg/day for six months experienced notable symptom relief.
Improvements in orientation, irritability reduction, and apathy management were observed in vascular dementia populations.
Application Fields
Dietary Supplements
Perfect for nootropic stacks, memory support capsules and brain health formulations for aged populations and students.
Sports Nutrition
Ideal for pre-workout powders, performance enhancing tablets and endurance solutions that need fast choline administration.
Functional Food & Drinks
It is GRAS approved in a number of markets for usage in coffee, tea, cereal bars, ready-to-eat cereals and chocolate goods.
Clinical Nutrition
Used in clinical nutrition for treatment of cognitive decline and in post-stroke rehabilitation procedures.
Quality Control
Our quality assurance system consists of raw material checks, in-process controls and completed product testing. Each batch is HPLC tested to verify that it meets the 98% purity standards.
Professional laboratory teams test for heavy metals (<10 ppm), residual solvents, microbiological pollutants and glycidol residues. Stability studies provide assurance of shelf-life reliability under approved storage settings.
Hygroscopic deterioration prevented by strict restrictions on humidity (<30% RH) in manufacture We keep comprehensive traceability paperwork from the source lecithin to the final packing.
|
Parameter |
Specification |
|
Content |
≥98% (HPLC) |
|
Appearance |
White to off-white fine powder |
|
CAS Number |
28319-77-9 |
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Solubility |
Freely soluble in water and ethanol |
|
Loss on Drying |
<1.0% |
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Heavy Metals |
<10 ppm |
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Storage |
Cool, dark, dry conditions |
Certificates
We hold ISO9001 Quality Management System Certification for α-GPC, ensuring standardized production processes. SGS third-party verification confirms our compliance with international safety standards.
HALAL certification meets requirements for specific regional markets. We provide COA, TDS, MSDS/SDS, stability reports, origin certificates, and allergen/GMO declarations upon request.
Additional Kosher certification is available for qualifying projects.
Payment & Shipment
Flexible payment terms accommodate various transaction scales. We accept bank transfers, letters of credit, and secure online payment methods.
Our global logistics network includes FedEx, DHL, EMS, UPS, TNT partnerships, plus air freight and ocean shipping options. For clients without import experience, we offer customs clearance assistance in Europe and the United States.
Products can be delivered directly to your facility with full tracking support and documentation coordination.
Packaging & Transportation
Standard packaging is double layer PE bags within aluminum foil bags or fiber drums shielding against exposure to moisture and light. Unique stability or branding needs are addressed using custom packaging solutions.
All shipments are IATA/IMDG compliant for secure international shipping. If circumstances in the surrounding environment threaten the integrity of the goods, we provide temperature-controlled logistics.
You may send numerous ingredients together using consolidated shipping services, which reduces the cost of freight and customs processes.
After-sales Service
Our experts help formulation improvement, dosage recommendations and regulatory paperwork. We answer questions in 24 hours and give troubleshooting support throughout your product development cycle.
Quality problems lead to prompt inquiry procedures and replacement or refund. Consults on inventory management and offers insight on market trends to long term clientele
Exhibitions
We attend important industry events such as Supply Side West, Vitafoods Europe and Fi Asia. These shows feature our newest product applications and allow technical conversations to begin immediately.
Stop by our booth to test samples and certification paperwork and discuss bespoke supply options with our expert staff.
Why Choose Us?
Direct Manufacturer Benefit
No middleman mark-ups factory-direct price. We may be flexible with MOQ for experimental formulations or for commercial volume manufacture.
Regulatory Awareness
Our ingredient has GRAS status in the U.S., Natural Health Product clearance in Canada and has been granted novel food ingredient status in China for 2024 (≤600 mg/day recommended consumption).
Complete Support
We take care of logistical complexity from procuring raw materials to customs clearance so you can concentrate on product creation. Our set of paperwork makes it simple to submit to different jurisdictions.
FAQ
Q : What is the mechanism of action of the product ? How does it differ from other choline sources such as citicoline and choline bitartrate?
A: The product is a water-soluble choline phospholipid derivative. Following oral ingestion , it is hydrolyzed to choline and glycerol-3-phosphate and reaches peak concentrations in one hour. It can permeate the blood brain barrier. The dual metabolic route supplies choline for acetylcholine production and glycerol-3-phosphate for phospholipid building and ATP generation. This makes it different from simple choline salts that merely deliver choline.
Q：What are the main health benefits of the product? What clinical research backs up these benefits?
A: Significant advantages include enhanced cognition, mood and sports performance. Meta-analyses show cognitive improvements in acute stroke patients and episodes of cerebrovascular dysfunction. A South Korean cohort study of 500,000+ patients aged 40+ showed reduced Alzheimer's risk. Athletic studies demonstrate that 600 mg/day for six days increased lower limb strength, while 250 mg/day for seven days improved vertical jump height and muscle power.
Q：What is the regulatory compliance status of the product? In which countries and regions has it been approved?
A：Japan approved it in food ingredient lists in 2009. The U.S. FDA granted GRAS status, allowing use in coffee, tea, cereal bars, chocolate, and over 400 products. Canada approved it for natural health products in 2023. China's National Health Commission approved it as a new food ingredient in March 2024 (Announcement No. 2), with ≤600 mg/day recommended intake (not for infants, children, pregnant or breastfeeding women).
Q：What documentation do you provide? What are your minimum order quantity and sample policies?
A：We supply COA, TDS, MSDS/SDS, stability reports, origin certificates, and allergen/GMO declarations. Kosher and Halal certifications are available when required. Our MOQ adapts to your project scale. We welcome sample requests—you cover only shipping costs—enabling quality checks and formulation trials before full commitment.
Contact Us
Ready to integrate premium α-GPC into your next formulation? Contact our team at sales@jayuanbio.com and sales1@jayuanbio.com for technical specifications, pricing, and sample requests.
