Dipotassium Glycyrrhizinate

Dipotassium Glycyrrhizinate

Specification:≥98%
Test Method: HPLC
Appearance:White or white like fine powder
CAS.:68797-35-3
Free sample:available
MOQ:1KG
Certification:KOSHER,HALAL,BRC,ORGANIC,ISO9001,ISO22000 etc.

Jayuan Bio—Your Trusted Partner ForDipotassium Glycyrrhizinat

Dipotassium Glycyrrhizinate is a widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to Dipotassium Glycyrrhizinate(DPG), which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of it. Therefore, it is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.Its related products are manufactured, packaged and stored under Jayuan Bio-tech, which has over 20 years' experience, two GMP working lines, and over 50 professional workers.

Dipotassium Glycyrrhizinate

Source of DPG

Licorice(Glycyrrhiza uralensis Fisch) is a traditional Chinese herb plant. It's mainly distributed in Northwest China, for example, Inner Mongolia, Gansu, Shanxi and some other places where there are also many merchants that cultiate the licorice. It contains many effective ingredients, such as liquiritin, glycyrrhizic acid, glycyrrhetinic acid, licorice flavonoids, liquiritigenin, etc. Because all the important ingredients are in the roots and bark, roots are the major medicinal sources. The main fields applied are the medical, health care products and cosmetics industries.

Difference With Glycyrrhizic Acid

 

DPG

Glycyrrhizic Acid

Source

Potassium derivatives of glycyrrhizic acid

Licorice root

Appearance

White powder

White crystalline powder

Molecular Structure

product-181-100

product-186-100

Solubility

Easily soluble in water, dilute ethanol, glycerol, propylene glycol; slightly soluble in anhydrous ethanol, ether.

Hard to be soluble in cold water; easily soluble in hot water; insoluble in grease; its hot water solution is gelatinous after cooling; soluble in propylene glycol.

Application

Whitening cosmetics, teeth care and hair care products

Food additives (Sweeteners, flavorings, flavor enhancers) and pharmaceuticals industry

Process of Extract

product-633-69

 

Importance in Wound Healing

One research has found alternative methods or compounds aimed to enhance skin healing processes, focusing on promoting epidermal and dermal regeneration. This compound is glycyrrhizic acid (GA), known for its antitumor, anti-allergic, antibiotic, and anti-inflammatory effects. DPG, a derivative of GA, has similar properties as anti-allergic, antibiotic, and anti-inflammatory as corticosteroids but without so many side effects such as allergic reactions.

Functions

  1. Skin-whitening: One research shows that DPG can inhibit tyrosinase activity and reduce melanin production, suggesting its potential as a skin lightening agent that helps prevent skin pigmentation.
  2. Anti-inflammatory: Some studies have demonstrated that it possesses anti-inflammatory properties. This makes it effective in reducing skin redness and alleviating irritation associated with conditions like rosacea and psoriasis. At the same time, its ability to regulate oil production helps inhibit excessive sebum secretion from the skin's sebaceous glands.
  3. Promote Wound Healing: The therapeutic impact of it primarily involves alleviating wound inflammation by reducing granulocyte counts. Additionally, it stimulates the formation of granulation tissue and enhances the rapid proliferation of fibroblasts. DPG also boosts the creation of new capillaries, expediting the tissue healing process.

Functions of Dipotassium Glycyrrhizinate

Applications

  1. Cosmetics Produce: It can easily be soluble in water, demonstrating excellent water solubility. It is also soluble in glycerol and propylene glycol. Its molecular structure includes both hydrophilic and lipophilic groups, enabling DPG to lower the surface tension of aqueous solutions, making it an effective surfactant. DPG possesses self-emulsifying properties and stabilizes emulsion, thereby reducing the need for additional emulsifiers in cosmetic formulations. It exhibits broad compatibility in various cosmetic formulations.
  2. Skin care: Anti-inflammatory-suitable for treatment of skin inflammation such as wounds, eczema, burns; care for sensitive, fragile and irritating skin. It can whiten our skin by inhibiting melanin production and brightening skin tones. As an anti-allergy, sunscreen, anti-freckle, whitening cosmetic functional additive, it can effectively prevent skin inflammation, and it has a sedative effect on inflammation caused by sunlight.
  3. Personal Care: It can relieve itchy scalp, and is used in the treatment of gingivitis; it can also help to maintain oral hygiene and provide dental protection.

Applications of Dipotassium Glycyrrhizinate

Certificates

Up to now, our company has possessed certification such as ISO, SGS, HALA, KOSHER, BRC, ORGANIC, ISO9001, ISO22000, etc.

Certificates

Why Choose Us?

  1. We have two GMP standard production lines. Our factory covers an area of 50,000 square meters, with the laboratory occupying over 1,000 square meters. With a professional R&D team of more than 30 people and over 60 quality analysis personnel, we ensure continuous innovation and stable product quality.
  2. Also, we collaborate with many pharmaceutical companies, and our product quality has been recognized through multiple tests. With over 20 years of experience, our products have been sold to more than 50 countries and over 3,000 companies worldwide, receiving consistent praise from customers.
  3. And we possess advanced testing equipment, including 3 Gas Chromatography of Shimadzu, 5 Liquid Chromatography of Shimadzu, 5 Agilent's Gas Chromatography, and supporting automatic polarimeter, Melting-Point-Measuring Instruments, acidimeter, pharmaceutical stability test box, Clarity Test Equipment , etc. These instruments meet our quality analysis needs from raw materials to intermediates and finished products.

Our Advantages

Contact Us

In conclusion, Dipotassium Glycyrrhizinate has many advantages for our body. For inquiries and more details, please contact us at sales@jayuanbio.com at any time!

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