Diacerein

Jayuan—A trusted Partner For High Quality Product

Diacerein, also referred to as diacetylrhein, belongs to the class of anthraquinone that is used to treat joint conditions like osteoarthritis, which involve joint swelling and pain. It is an anthraquinone derivative found in cinnamomum with natural anti-inflammatory properties, which has anti-inflammatory and protective effects on articular cartilage. Although the action is slower, the damage to our health is lower than other drugs. A comprehensive review by Cochrane in 2014 indicated that it can provide a modest pain-relieving effect. Medications contained it are approved in certain European Union and Asian countries and are recommended as a treatment in various international therapeutic guidelines.

Jayuan Bio has over 20 years experience in researching it, and with two GMP working line and more than 30 professional workers, Jayuan can produce high quality product and customized products for different needs.

Related Studies

In one research in 2013, they studied osteoarthritis patients who taking it. Result shows that patients have improved pain slightly, and enhanced their physical function. At the same time, the pill can slow the process of joint space narrowing slightly. With this product, osteoarthritis patients have improved their life quality to some extent.

Acute kidney injury (AKI) is a crucial clinical disorder and a huge health problem all over the world.

Many studies have been conducted to confirm the protective role of diacerein and its active metabolite rhein in AKI. Researchers found the antioxidant protective effect of rhein on acetaminophen-induced hepatotoxicity and nephrotoxicity in rats.

Another study of AKI showed that functional and structural changes in the kidney were significantly attenuated by modulating inflammation, oxidative stress, apoptosis and necroptosis with diacerein.

Market Preview

With increasing demand for pain management solutions, the market for analgesic and anti-inflammatory drugs is expanding. With the aging problem growing, the incidence of rheumatoid arthritis, osteoarthritis, and other types of arthritis is increasing. Diacerein, as an important NSAID, will have a broad market. At the same time, being a treatment of musculoskeletal pain, sprains, and muscle inflammation, will have an increasing demand. Also, due to population growth and improvements in basic medical equipment, it will become more and more important in the Asia market.

Functions

1. Gastrointestinal protection: One research shows that it can inhibit the production of ROS. Therefore, it can relieve the symptoms and is anti-inflammatory caused by gastric ulceration.
2. Anti-cancer: There is a lot of evidence that has shown that it can be a treatment for preventing cancer. In a recent study, IL-6 was a common cause of cancer, like breast cancer. however, it can inhibit the production of IL-6, and reduce the production of cancer cells.
3. Hepatoprotective effect: In a recent experiment between non-alcoholic fatty liver patients and T2DM disease that used it. After a month, their life stiffness was significantly decreased and reflected fibrosis diminution a lot.
4. Synergetic agent: Another important study of it is the combination study. Together with febuxostat drug can enhance the effect to refractory gout; Another study suggests that a combined treatment may be useful in treating diabetic nephropathy compared with the therapeutic effects of single treatment.

Application

1. Treatment for Joint Disease: It can treat joint conditions such as arthritis and osteoarthritis, and relieve joint pain and inflammation. At the same time, it can induce chondrogenesis and has analgesic, anti-inflammatory and antipyretic effects.
2. Topical Use: It is also applied in forms such as gel and cream for some treatment. Usually is for muscle and skeletal pain, and inflammation and discomfort that caused by other injuries.
3. Treatment for Type2 Diabetes: In some experiments, scientists found that it can lower the increase of insulin by inhibiting the increase of L-1βand TNF-α.
4. Anti-cancer Treatment: It can decrease the viability of cancer cells, and it can inhibit breast cancer cells like MCF-7, MDA-MB-231 and T47D, which offer a new treatment for breast cancer patients.
5. Periodontal Treatment: It can relieve inflammatory pain and symptoms caused by pro-inflammatory cytokines such as 1L-6, 1L-1 and TNF-α.

Certificates

Up to now, the company has possessed the ISO, SGS, HALA, KOSHER, BRC, ORGANIC, ISO9001, ISO22000, etc certification.

Why Choose Us?

1. Quality Priority: Jiayuan values product quality and safety, ensuring that the purity and content of active ingredients in extracts meet standards, thereby establishing a good reputation and brand image.
2. Technological Innovation: Continuous investment in research and development to develop new extraction technologies and processes, improving extraction efficiency and product quality, and constantly introducing competitive new products.
3. In-house Manufacturing: With the advantage of owning in-house factories, we can better control the production process and quality, thus improving production efficiency and product stability.
4. Supply Chain Advantage: We have established a stable raw material supply chain and long-term partnerships with plant cultivation bases and suppliers to ensure stable supply of raw materials and controllable quality.

Contact Us

In conclusion, Diacerein has many advantages for our body. For inquiries, please contact us at sales@jayuanbio.com.